Frasier: Get a First Look at Season 2's Starry Guest Lineup — Including Peri Gilpin's Return as Roz! (Exclusive)

Mar. 15, 2025

Patricia Heaton and Kelsey Grammer on ‘Frasier.'.Photo:Chris Haston/Paramount+

Chris Haston/Paramount+

The good doctor is back — and with some famous friends!In just a week,Kelsey Grammerwill step back into the iconic role of Dr. Frasier Crane for season 2 ofFrasier,which premieres on Sept. 19.While the Paramount+ revival’s first go-around welcomed back two familiar faces —Bebe Neuwirthas Dr. Crane’s thorny ex Lilith and Peri Gilpin as his former radio show producer Roz — this new season promises a star-studded lineup of guest stars to help keep the laughter flowing, includingPatricia Heaton,Yvette Nicole Brown,Rachel Bloom,Amy Sedaris,Carol Burnett, Harriet Sansom Harris, Edward Hibbert, Dan Butler and Kelsey’s daughterGreer Grammer.Gilpin is also set to return again in the same role that made her so beloved with fans.Below, PEOPLE has the exclusive first look at the celebrity guest stars appearing on the comedy in the coming months.

The good doctor is back — and with some famous friends!

In just a week,Kelsey Grammerwill step back into the iconic role of Dr. Frasier Crane for season 2 ofFrasier,which premieres on Sept. 19.

While the Paramount+ revival’s first go-around welcomed back two familiar faces —Bebe Neuwirthas Dr. Crane’s thorny ex Lilith and Peri Gilpin as his former radio show producer Roz — this new season promises a star-studded lineup of guest stars to help keep the laughter flowing, includingPatricia Heaton,Yvette Nicole Brown,Rachel Bloom,Amy Sedaris,Carol Burnett, Harriet Sansom Harris, Edward Hibbert, Dan Butler and Kelsey’s daughterGreer Grammer.

Gilpin is also set to return again in the same role that made her so beloved with fans.

Below, PEOPLE has the exclusive first look at the celebrity guest stars appearing on the comedy in the coming months.

01of 10A Casual ToastJess Salgueiro, Jack Cutmore-Scott, Peri Gilpin, Patricia Heaton and Kelsey Grammer in season 2, episode 9 of ‘Frasier.'.Chris Haston/Paramount+In the season 1 finale, Roz (Peri Gilpin) paid Frasier an unexpected visit during his Christmas party but decides to stick around Boston a little longer.Here, the former producer returns for season 2 and finds herself locked in conversation with Eve (Jess Salgueiro), Freddy (Jack Cutmore-Scott), Holly (Patricia Heaton) and Frasier.

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A Casual Toast

Jess Salgueiro, Jack Cutmore-Scott, Peri Gilpin, Patricia Heaton and Kelsey Grammer in season 2, episode 9 of ‘Frasier.'.Chris Haston/Paramount+

In the season 1 finale, Roz (Peri Gilpin) paid Frasier an unexpected visit during his Christmas party but decides to stick around Boston a little longer.

Here, the former producer returns for season 2 and finds herself locked in conversation with Eve (Jess Salgueiro), Freddy (Jack Cutmore-Scott), Holly (Patricia Heaton) and Frasier.

02of 10

Talk to the Hand

Patricia Heaton and Kelsey Grammer in season 2 episode 9 of ‘Frasier.'.Chris Haston/Paramount+

This time around, the two-time Emmy-winning actress plays Holly, a “down-to-earth” and “unpretentious” Boston native who tends bar at restaurants and events.

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Turning the Tables

Kelsey Grammer and Patricia Heaton in season 2 episode 9 of ‘Frasier.'.Chris Haston/Paramount+

04of 10Sharing a ChuckleKelsey Grammer and Amy Sedaris in season 2 episode 4 of ‘Frasier.'.Chris Haston/Paramount+Amy Sedarisportrays Dr. “Doc” Stathos, a municipal therapist with a down home, scattered veneer who works with the firefighters at Freddy’s firehouse. She also happens to be a huge fan of Frasier’s from his radio show days.

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Sharing a Chuckle

Kelsey Grammer and Amy Sedaris in season 2 episode 4 of ‘Frasier.'.Chris Haston/Paramount+

Amy Sedarisportrays Dr. “Doc” Stathos, a municipal therapist with a down home, scattered veneer who works with the firefighters at Freddy’s firehouse. She also happens to be a huge fan of Frasier’s from his radio show days.

05of 10What a Surprise!Yvette Nicole Brown, Toks Olagundoye and Rafael Cebrián in season 2 episode 7 of ‘Frasier.'.Chris Haston/Paramount+After Olivia (Toks Olagundoye) name-dropped her sister several times during season 1, Monica (Yvette Nicole Brown) finally pops up this season. But she may be in for an unexpected surprise or two.

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What a Surprise!

Yvette Nicole Brown, Toks Olagundoye and Rafael Cebrián in season 2 episode 7 of ‘Frasier.'.Chris Haston/Paramount+

After Olivia (Toks Olagundoye) name-dropped her sister several times during season 1, Monica (Yvette Nicole Brown) finally pops up this season. But she may be in for an unexpected surprise or two.

06of 10Deliciously DeviousHarriet Sansom Harris in season 2 episode 5 of ‘Frasier.'.Chris Haston/Paramount+Once described on the original NBC sitcom as “Lady Macbeth without the sincerity,” Frasier’s agent Bebe Glazer (Harriet Sansom Harris) was arguably one of the show’s smartest-written recurring characters.Episode 5 ofFrasiersees the delectable return of Bebe with a Bloody Mary cocktail in hand.

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Deliciously Devious

Harriet Sansom Harris in season 2 episode 5 of ‘Frasier.'.Chris Haston/Paramount+

Once described on the original NBC sitcom as “Lady Macbeth without the sincerity,” Frasier’s agent Bebe Glazer (Harriet Sansom Harris) was arguably one of the show’s smartest-written recurring characters.

Episode 5 ofFrasiersees the delectable return of Bebe with a Bloody Mary cocktail in hand.

07of 10Like Mother, Like Daughter?Kelsey Grammer, Rachel Gloom and Harriet Sansom Harris in season 2 episode 5 of ‘Frasier.'.Chris Haston/Paramount+Bebe’s reunion with Frasier includes an introduction to her daughter Phoebe Glazer (Rachel Bloom).Bloom toldEntertainment Weeklyher character is a “very cultured kind of opera fan.““She and Frasier hit it off in a way that he questions if maybe they’re related,” Bloom teased.

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Like Mother, Like Daughter?

Kelsey Grammer, Rachel Gloom and Harriet Sansom Harris in season 2 episode 5 of ‘Frasier.'.Chris Haston/Paramount+

Bebe’s reunion with Frasier includes an introduction to her daughter Phoebe Glazer (Rachel Bloom).

Bloom toldEntertainment Weeklyher character is a “very cultured kind of opera fan.”

“She and Frasier hit it off in a way that he questions if maybe they’re related,” Bloom teased.

08of 10

Being a Father

Kelsey Grammer, Greer Grammer, Jack Cutmore-Scott and Jess Salgueiro in season 2 episode 6 of ‘Frasier.'.Chris Haston/Paramount+

While Alice is all grown-up now, that doesn’t stop Frasier from being a little paternal and helping her take off her coat.

09of 10A Reunion of Radio JockeysDan Butler and Kelsey Grammer in season 2 episode 8 of ‘Frasier.'.Chris Haston/Paramount+As host of the Gonzo Sports Show on KACL radio on the originalFrasier, Bob “Bulldog” Brisco (Dan Butler) couldn’t be more different from the good doctor.But the two have eked out a begrudging respect, and in episode 8, Bulldog and Frasier reconnect at KACL radio.

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A Reunion of Radio Jockeys

Dan Butler and Kelsey Grammer in season 2 episode 8 of ‘Frasier.'.Chris Haston/Paramount+

As host of the Gonzo Sports Show on KACL radio on the originalFrasier, Bob “Bulldog” Brisco (Dan Butler) couldn’t be more different from the good doctor.

But the two have eked out a begrudging respect, and in episode 8, Bulldog and Frasier reconnect at KACL radio.

10of 10Just Like Old TimesKelsey Grammer, Edward Hibbert, Dan Butler and Peri Gilpin in season 2 episode 8 of ‘Frasier.'.Chris Haston/Paramount+In a full circle moment, Frasier finds himself in his old recording booth at KACL radio with Roz, Bulldog and food critic Gil Chesterson (Edward Hibbert), who hosted the radio show “Restaurant Beat” on the original sitcom.

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Just Like Old Times

Kelsey Grammer, Edward Hibbert, Dan Butler and Peri Gilpin in season 2 episode 8 of ‘Frasier.'.Chris Haston/Paramount+

In a full circle moment, Frasier finds himself in his old recording booth at KACL radio with Roz, Bulldog and food critic Gil Chesterson (Edward Hibbert), who hosted the radio show “Restaurant Beat” on the original sitcom.

Never miss a story — sign up forPEOPLE’s free daily newsletterto stay up-to-date on the best of what PEOPLE has to offer​​, from celebrity news to compelling human interest stories.Season 2 ofFrasierpremieres Thursday, Sept. 19 on Paramount+.

Never miss a story — sign up forPEOPLE’s free daily newsletterto stay up-to-date on the best of what PEOPLE has to offer​​, from celebrity news to compelling human interest stories.

Season 2 ofFrasierpremieres Thursday, Sept. 19 on Paramount+.

source: people.com